Version 5.4
| Mus musculus Protein: Npy6r | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-144417.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Npy6r | ||||||||
| Protein Name | neuropeptide Y receptor Y6 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000040797 | ||||||||
| InnateDB Gene | IDBG-144415 (Npy6r) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY = PYY >= NPY (2-36) = [Leu-31, Pro-34] NPY > NPY (13-36) > PP. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity. | ||||||||
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Kidney and discrete regions of the hypothalamus including the suprachiasmatic nucleus, anterior hypothalamus, bed nucleus stria terminalis, and the ventromedial nucleus. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1098590 | ||||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR000351 Neuropeptide Y1 receptor IPR000611 Neuropeptide Y receptor family IPR000986 Neuropeptide Y6 receptor IPR001556 Bombesin receptor IPR017452 GPCR, rhodopsin-like, 7TM |
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| PFAM |
PF00001
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| PRINTS |
PR00237
PR01013 PR01012 PR01017 PR00358 |
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q61212 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 18169 | ||||||||
| UniGene | Mm.57234 | ||||||||
| RefSeq | NP_035065 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Npy6r | ||||||||
| OMIM | |||||||||
| CCDS | CCDS29227 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK030279 BC103620 BC103621 BC103622 BC103667 U58367 U59430 | ||||||||
| GenPept | AAB18624 AAB19188 AAI03621 AAI03622 AAI03623 AAI03668 BAC26875 | ||||||||