Version 5.4
Mus musculus Protein: Mettl21d
Summary
InnateDB Protein IDBP-144584.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mettl21d
Protein Name methyltransferase like 21D
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000055002
InnateDB Gene IDBG-144582 (Mettl21d)
Protein Structure
UniProt Annotation
Function Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016279 protein-lysine N-methyltransferase activity
Biological Process
GO:0018023 peptidyl-lysine trimethylation
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2684917
InterPro IPR019410 Nicotinamide N-methyltransferase-like
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF10294
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C436
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 207965
UniGene Mm.102487
RefSeq NP_001028408
MGI ID
MGI Symbol Vcpkmt
OMIM
CCDS CCDS36464
HPRD
IMGT
EMBL AK083148 AK144832 BC138942 BC138943
GenPept AAI38943 AAI38944 BAC38784 BAE26088

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca