Version 5.4
Mus musculus Protein: Mnx1
Summary
InnateDB Protein IDBP-144593.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mnx1
Protein Name motor neuron and pancreas homeobox 1
Synonyms HB9; Hlxb9; MNR2;
Species Mus musculus
Ensembl Protein ENSMUSP00000001608
InnateDB Gene IDBG-144591 (Mnx1)
Protein Structure
UniProt Annotation
Function Putative transcription factor involved in pancreas development and function.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001764 neuron migration
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008045 motor neuron axon guidance
GO:0009791 post-embryonic development
GO:0021520 spinal cord motor neuron cell fate specification
GO:0021675 nerve development
GO:0021904 dorsal/ventral neural tube patterning
GO:0021953 central nervous system neuron differentiation
GO:0030182 neuron differentiation
GO:0031016 pancreas development
GO:0031018 endocrine pancreas development
GO:0048667 cell morphogenesis involved in neuron differentiation
GO:0048812 neuron projection morphogenesis
GO:0060539 diaphragm development
GO:0060541 respiratory system development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:109160
InterPro IPR001356 Homeobox domain
IPR003072 Orphan nuclear receptor, NOR1 type
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR01286
PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QZW9
PhosphoSite PhosphoSite-Q9QZW9
TrEMBL
UniProt Splice Variant
Entrez Gene 15285
UniGene Mm.484672
RefSeq
MGI ID
MGI Symbol Mnx1
OMIM
CCDS
HPRD
IMGT
EMBL AC164700 AF153046
GenPept AAD49613

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca