Version 5.4
Mus musculus Protein: Cd6
Summary
InnateDB Protein IDBP-145048.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd6
Protein Name CD6 antigen
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000079172
InnateDB Gene IDBG-145044 (Cd6)
Protein Structure
UniProt Annotation
Function Involved in cell adhesion. Binds to CD166.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed predominantly in thymus, lymph node and spleen.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0007155 cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:103566
InterPro IPR001190 SRCR domain
IPR017448 SRCR-like domain
PFAM PF00530
PRINTS PR00258
PIRSF
SMART SM00202
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q61003
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 12511
UniGene Mm.290897
RefSeq NP_033982
MGI ID
MGI Symbol Cd6
OMIM
CCDS CCDS37917
HPRD
IMGT
EMBL AK030822 AK030823 U12434 U37543 U37544
GenPept AAA64867 AAA81383 AAA81384 BAC27147 BAC27148

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca