InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gpc4

Summary

InnateDB Protein

IDBP-145157.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpc4

Protein Name

glypican 4

Synonyms

9530073D23Rik; AF311610; AI385680; AI661372; K-glypican;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033450

InnateDB Gene

IDBG-145155 (Gpc4)

Protein Structure

UniProt Annotation

Function

Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system.

Subcellular Localization

Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.Secreted glypican-4: Secreted, extracellular space {ECO:0000250}.

Disease Associations

Tissue Specificity

Highly expressed in developing brain and kidney.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0043395	heparan sulfate proteoglycan binding

Biological Process

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005796	Golgi lumen
GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0031225	anchored component of membrane
GO:0070062	extracellular vesicular exosome