Version 5.4
Mus musculus Protein: Atp6v0e2
Summary
InnateDB Protein IDBP-145160.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp6v0e2
Protein Name ATPase, H+ transporting, lysosomal V0 subunit E2
Synonyms 0610006O14Rik; NM9.2;
Species Mus musculus
Ensembl Protein ENSMUSP00000044110
InnateDB Gene IDBG-145158 (Atp6v0e2)
Protein Structure
UniProt Annotation
Function Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015078 hydrogen ion transmembrane transporter activity
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0015991 ATP hydrolysis coupled proton transport
Cellular Component
GO:0016021 integral component of membrane
GO:0033179 proton-transporting V-type ATPase, V0 domain
Protein Structure and Domains
PDB ID MGI:1923502
InterPro IPR008389 ATPase, V0 complex, subunit e1/e2
IPR017385 ATPase, V0 complex, subunit e1/e2, metazoa
PFAM PF05493
PRINTS
PIRSF PIRSF038097
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91XE7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 76252
UniGene Mm.474738
RefSeq NP_598525
MGI ID
MGI Symbol Atp6v0e2
OMIM
CCDS CCDS20103
HPRD
IMGT
EMBL BC010790
GenPept AAH10790

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca