Version 5.4
Mus musculus Protein: Slc16a10
Summary
InnateDB Protein IDBP-145169.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc16a10
Protein Name solute carrier family 16 (monocarboxylic acid transporters), member 10
Synonyms 2610103N14Rik; 9830169E08; Mct10; PRO0813; TAT1;
Species Mus musculus
Ensembl Protein ENSMUSP00000090227
InnateDB Gene IDBG-145167 (Slc16a10)
Protein Structure
UniProt Annotation
Function Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells. {ECO:0000269PubMed:16245314}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:16245314}; Multi-pass membrane protein {ECO:0000269PubMed:16245314}. Basolateral cell membrane {ECO:0000269PubMed:16245314}. Note=Detected in basolateral membrane of kidney proximal tubule starting at he beginning of the proximal tubule epithelium within the glomerular capsule and extending to the S1 and S2 segments. Localizes also to the basolateral membrane of small intestine enterocytes and to sinusoidal side of perivenous hepatocytes.
Disease Associations
Tissue Specificity Highly expressed in small intestine, particularly in jejunum and ileum, scarcely in colon and substantially in kidney, liver and skeletal muscle. {ECO:0000269PubMed:16245314}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Protein Structure and Domains
PDB ID MGI:1919722
InterPro IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain
PFAM PF07690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3U9N9
PhosphoSite PhosphoSite-Q3U9N9
TrEMBL
UniProt Splice Variant
Entrez Gene 72472
UniGene Mm.412639
RefSeq NP_082523
MGI ID
MGI Symbol Slc16a10
OMIM
CCDS CCDS48543
HPRD
IMGT
EMBL AK050229 AK151290 AK151704 AK157355 AK165240 AK165579
GenPept BAC34135 BAE30275 BAE30627 BAE34061 BAE38097 BAE38270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca