InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kctd5

Summary

InnateDB Protein

IDBP-145191.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kctd5

Protein Name

potassium channel tetramerisation domain containing 5

Synonyms

2610030N08Rik; mKIAA0176;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000017090

InnateDB Gene

IDBG-145189 (Kctd5)

Protein Structure

UniProt Annotation

Function

Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytosol {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0032403	protein complex binding

Biological Process

GO:0008150	biological_process
GO:0051260	protein homooligomerization

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

MGI:1916509

InterPro

IPR000210 BTB/POZ-like
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR011333 BTB/POZ fold

PFAM

PF02214

PRINTS

PIRSF

SMART

SM00225

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8VC57

PhosphoSite

PhosphoSite-Q8VC57

TrEMBL

UniProt Splice Variant

Entrez Gene

69259

UniGene

Mm.28171

RefSeq

NP_081284

MGI ID

MGI Symbol

Kctd5

OMIM

CCDS

CCDS28473

HPRD

IMGT

EMBL

AK143644 AY162410 BC021777

GenPept

AAH21777 AAO17163 BAE25476