Version 5.4
Mus musculus Protein: Fem1c
Summary
InnateDB Protein IDBP-145238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fem1c
Protein Name fem-1 homolog c (C.elegans)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000038816
InnateDB Gene IDBG-145236 (Fem1c)
Protein Structure
UniProt Annotation
Function Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed. Expressed at higher level in testis. {ECO:0000269PubMed:14527725}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2444737
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CEF1
PhosphoSite PhosphoSite-Q8CEF1
TrEMBL B2RRW5
UniProt Splice Variant
Entrez Gene 240263
UniGene Mm.409949
RefSeq NP_775599
MGI ID
MGI Symbol Fem1c
OMIM
CCDS CCDS29231
HPRD
IMGT
EMBL AK028330 AK049336 AK129440 AK147729 AY249189 BC138604 BC138605 CH466528
GenPept AAI38605 AAI38606 AAO64430 BAC25884 BAC33691 BAC98250 BAE28099 EDL09981

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca