InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sohlh2

Summary

InnateDB Protein

IDBP-145329.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sohlh2

Protein Name

spermatogenesis and oogenesis specific basic helix-loop-helix 2

Synonyms

4933406N12Rik; AI413378;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029369

InnateDB Gene

IDBG-145327 (Sohlh2)

Protein Structure

UniProt Annotation

Function

Probable transcription factor, which may be involved in spermatogenesis and oogenesis. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981, ECO:0000269PubMed:16765102}.

Disease Associations

Tissue Specificity

Preferentially expressed in the adult ovary and testis. {ECO:0000269PubMed:16564520, ECO:0000269PubMed:16765102}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0046983	protein dimerization activity

Biological Process

GO:0001545	primary ovarian follicle growth
GO:0006351	transcription, DNA-templated
GO:0007283	spermatogenesis
GO:0009994	oocyte differentiation
GO:0010468	regulation of gene expression
GO:0045944	positive regulation of transcription from RNA polymerase II promoter