InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tmem109

Summary

InnateDB Protein

IDBP-145397.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tmem109

Protein Name

transmembrane protein 109

Synonyms

1110006I15Rik; AA958958; C77652;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039529

InnateDB Gene

IDBG-145395 (Tmem109)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Nucleus outer membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Sarcoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0060548	negative regulation of cell death
GO:0071480	cellular response to gamma radiation

Cellular Component

GO:0005640	nuclear outer membrane
GO:0005737	cytoplasm
GO:0016021	integral component of membrane
GO:0031965	nuclear membrane
GO:0033017	sarcoplasmic reticulum membrane
GO:0070062	extracellular vesicular exosome