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InnateDB Protein
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IDBP-145556.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Npdc1
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Protein Name
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neural proliferation, differentiation and control gene 1
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Synonyms
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AI314472; NPDC-1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000071387
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InnateDB Gene
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IDBG-145554 (Npdc1)
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Protein Structure
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| Function |
Suppresses oncogenic transformation in neural and non- neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation.
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| Subcellular Localization |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
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| Disease Associations |
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| Tissue Specificity |
Expressed in the brain and nervous system. Not detected in liver, heart, skeletal muscle, spleen, pancreas, pituitary and adrenal glands. Expression increases when cultured neural cells are growth-arrested and begin to differentiate.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
12 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:1099802
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| InterPro |
IPR009635
Neural proliferation differentiation control-1
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| PFAM |
PF06809
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q64322
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| PhosphoSite |
PhosphoSite-Q64322
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
18146
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| UniGene |
Mm.471344
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| RefSeq |
NP_032747
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| MGI ID |
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| MGI Symbol |
Npdc1
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| OMIM |
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| CCDS |
CCDS15771
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| HPRD |
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| IMGT |
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| EMBL |
AK146466
AL732557
BC003320
CH466542
L03814
X67209
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| GenPept |
AAA39836
AAH03320
BAE27193
CAA47648
CAM25615
EDL08243
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Version 5.4