InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Camk2n2

Summary

InnateDB Protein

IDBP-145561.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Camk2n2

Protein Name

calcium/calmodulin-dependent protein kinase II inhibitor 2

Synonyms

2900075A18Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000057368

InnateDB Gene

IDBG-145559 (Camk2n2)

Protein Structure

UniProt Annotation

Function

Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2 (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus. Cytoplasm, cytosol. Note=Excluded from nucleus when coexpressed with activated CAMK2. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008427	calcium-dependent protein kinase inhibitor activity
GO:0019901	protein kinase binding

Biological Process

GO:0006469

negative regulation of protein kinase activity

Cellular Component

GO:0005575	cellular_component
GO:0005634	nucleus
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:1920297

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q78WH7

PhosphoSite

PhosphoSite-Q78WH7

TrEMBL

B2RXL5

UniProt Splice Variant

Entrez Gene

73047

UniGene

Mm.437414

RefSeq

NP_082696

MGI ID

MGI Symbol

Camk2n2

OMIM

CCDS

CCDS49795

HPRD

IMGT

EMBL

AK013788 BC147550 BC147736 BC147745 BC157896 CH466521

GenPept

AAI47551 AAI47737 AAI47746 AAI57897 BAB28995 EDK97583