Mus musculus Protein: Gimap5
Summary
InnateDB Protein IDBP-145644.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gimap5
Protein Name GTPase, IMAP family member 5
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000056820
InnateDB Gene IDBG-145642 (Gimap5)
Protein Structure
UniProt Annotation
Function Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion outer membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Lysosome {ECO:0000269PubMed:21487483}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005525 GTP binding
Biological Process
Cellular Component
GO:0005741 mitochondrial outer membrane
GO:0005764 lysosome
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2442232
InterPro IPR006703 AIG1
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF04548
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BWF2
PhosphoSite PhosphoSite-Q8BWF2
TrEMBL
UniProt Splice Variant
Entrez Gene 317757
UniGene Mm.455917
RefSeq NP_778200
MGI ID
MGI Symbol Gimap5
OMIM
CCDS CCDS20114
HPRD
IMGT
EMBL AB126961 AK052694 BC095995
GenPept AAH95995 BAC35100 BAD06929