Version 5.4
Mus musculus Protein: Fut7
Summary
InnateDB Protein IDBP-145685.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fut7
Protein Name fucosyltransferase 7
Synonyms AI853193; FTVII; Fuc-TVII; FucT-VII;
Species Mus musculus
Ensembl Protein ENSMUSP00000097895
InnateDB Gene IDBG-145681 (Fut7)
Protein Structure
UniProt Annotation
Function May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens.
Subcellular Localization Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Disease Associations
Tissue Specificity Highly expressed in lung and bone marrow and to a much lesser extent in spleen, salivary gland and skeletal muscle.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008417 fucosyltransferase activity
Biological Process
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0002522 leukocyte migration involved in immune response
GO:0006486 protein glycosylation
GO:0036065 fucosylation
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID MGI:107692
InterPro IPR001503 Glycosyl transferase, family 10
PFAM PF00852
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q11131
PhosphoSite PhosphoSite-Q11131
TrEMBL E2D0W5
UniProt Splice Variant
Entrez Gene 14347
UniGene Mm.1203
RefSeq NP_001276384
MGI ID
MGI Symbol Fut7
OMIM
CCDS CCDS50530
HPRD
IMGT
EMBL BC105670 GQ424192 U45980
GenPept AAC52484 AAC52485 AAI05671 ADK94359

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca