Version 5.4
Mus musculus Protein: Rab11fip1
Summary
InnateDB Protein IDBP-145770.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rab11fip1
Protein Name RAB11 family interacting protein 1 (class I)
Synonyms 2010200K21Rik; 4833414G05Rik; Rcp;
Species Mus musculus
Ensembl Protein ENSMUSP00000033878
InnateDB Gene IDBG-145768 (Rab11fip1)
Protein Structure
UniProt Annotation
Function A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and phagocytosis (By similarity). {ECO:0000250}.
Subcellular Localization Recycling endosome {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Note=Membrane-bound. RAB11A rather than RAB4A mediates RAB11FIP1 localization in the endocytic recycling compartment (ERC). Colocalizes with RAB11A at phagosomes (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0015031 protein transport
Cellular Component
GO:0030670 phagocytic vesicle membrane
GO:0055037 recycling endosome
Protein Structure and Domains
PDB ID MGI:1923017
InterPro IPR000008 C2 domain
IPR019018 Rab-binding domain FIP-RBD
PFAM PF00168
PF09457
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D620
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 75767
UniGene Mm.205335
RefSeq NP_083699
MGI ID
MGI Symbol Rab11fip1
OMIM
CCDS CCDS52534
HPRD
IMGT
EMBL AK014696 AK151024 BC125400 BC132094 CH466580
GenPept AAI25401 AAI32095 BAB29507 BAE30042 EDL32793

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca