InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Meis3

Summary

InnateDB Protein

IDBP-146063.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Meis3

Protein Name

Meis homeobox 3

Synonyms

AI573393; Mrg2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000002495

InnateDB Gene

IDBG-146061 (Meis3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed at high levels in the brain. Significant expression also observed in the heart, spleen and lung.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051897	positive regulation of protein kinase B signaling
GO:2001234	negative regulation of apoptotic signaling pathway