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InnateDB Protein
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IDBP-146153.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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2410003K15Rik
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Protein Name
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RIKEN cDNA 2410003K15 gene
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Synonyms
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2410003K15Rik; Matsu1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000031839
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InnateDB Gene
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IDBG-146151 (2410003K15Rik)
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Protein Structure
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| Function |
May function as a ribosomal silencing factor. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Mitochondrion matrix. Note=Colocalizes with MRPL12 and/or MRPL14. {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
4 [view]
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Molecular Function |
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| Biological Process |
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GO:0042273
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ribosomal large subunit biogenesis
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GO:0070130
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negative regulation of mitochondrial translation
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| Cellular Component |
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| PDB ID |
MGI:1922843
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| InterPro |
IPR004394
Protein Iojap/ribosomal silencing factor RsfS
IPR025656
Oligomerisation domain
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| PFAM |
PF02410
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q9CWV0
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| PhosphoSite |
PhosphoSite-Q9CWV0
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
75593
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| UniGene |
Mm.439947
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| RefSeq |
NP_083629
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| MGI ID |
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| MGI Symbol |
Malsu1
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| OMIM |
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| CCDS |
CCDS51768
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| HPRD |
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| IMGT |
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| EMBL |
AK010366
AK031878
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| GenPept |
BAB26886
BAC27589
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Version 5.4