InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tmem14c

Summary

InnateDB Protein

IDBP-146575.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tmem14c

Protein Name

transmembrane protein 14C

Synonyms

1110021D01Rik; AU020193; HSPC194;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000021790

InnateDB Gene

IDBG-146573 (Tmem14c)

Protein Structure

UniProt Annotation

Function

Required for normal heme biosynthesis. {ECO:0000250}.

Subcellular Localization

Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006783	heme biosynthetic process
GO:0008150	biological_process

Cellular Component

GO:0005739	mitochondrion
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

MGI:1913404

InterPro

IPR005349 Uncharacterised protein family UPF0136, Transmembrane

PFAM

PF03647

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CQN6

PhosphoSite

PhosphoSite-Q9CQN6

TrEMBL

Q8C297

UniProt Splice Variant

Entrez Gene

66154

UniGene

Mm.387141

RefSeq

NP_079663

MGI ID

MGI Symbol

Tmem14c

OMIM

CCDS

CCDS26470

HPRD

IMGT

EMBL

AK003891 AK008495 AK008878 AK010609 AK012101 AK019395 AK050688 AK089021 BC025854 BC055862 CH466546

GenPept

AAH25854 AAH55862 BAB23060 BAB25700 BAB25946 BAB27059 BAB28032 BAB31700 BAC34380 BAC40705 EDL40965