Mus musculus Protein: Tmeff1
Summary
InnateDB Protein IDBP-146700.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmeff1
Protein Name transmembrane protein with EGF-like and two follistatin-like domains 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000030032
InnateDB Gene IDBG-146698 (Tmeff1)
Protein Structure
UniProt Annotation
Function May inhibit NODAL and BMP signaling during neural patterning. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain, neurointermediate lobe, pars distalis, pancreas, ovary and testis. {ECO:0000269PubMed:11025219, ECO:0000269PubMed:11165370}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1926810
InterPro IPR000742 Epidermal growth factor-like domain
IPR002350 Kazal domain
PFAM PF00008
PF00050
PF07648
PRINTS
PIRSF
SMART SM00181
SM00280
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PFE7
PhosphoSite PhosphoSite-Q6PFE7
TrEMBL
UniProt Splice Variant
Entrez Gene 230157
UniGene Mm.422686
RefSeq NP_067411
MGI ID
MGI Symbol Tmeff1
OMIM
CCDS CCDS18168
HPRD
IMGT
EMBL AJ400622 AK043792 AK079633 AL772151 AL807771 BC057598
GenPept AAH57598 BAC31655 BAC37709 CAB90827 CAM15043 CAM15044 CAM20710 CAM20711