Version 5.4
Mus musculus Protein: Eaf1
Summary
InnateDB Protein IDBP-146770.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eaf1
Protein Name ELL associated factor 1
Synonyms 4933403C17Rik; AI666536;
Species Mus musculus
Ensembl Protein ENSMUSP00000022446
InnateDB Gene IDBG-146768 (Eaf1)
Protein Structure
UniProt Annotation
Function Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. {ECO:0000250}.
Subcellular Localization Nucleus, Cajal body {ECO:0000250}. Nucleus speckle {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0015030 Cajal body
GO:0016607 nuclear speck
GO:0032783 ELL-EAF complex
Protein Structure and Domains
PDB ID MGI:1921677
InterPro IPR019194 Transcription elognation factor Eaf, N-terminal
PFAM PF09816
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D4C5
PhosphoSite PhosphoSite-Q9D4C5
TrEMBL
UniProt Splice Variant
Entrez Gene 74427
UniGene Mm.490519
RefSeq NP_083208
MGI ID
MGI Symbol Eaf1
OMIM
CCDS CCDS26914
HPRD
IMGT
EMBL AK016628 AK044181 AK044737 BC079658
GenPept AAH79658 BAB30346 BAC31806 BAC32058

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca