Version 5.4
Mus musculus Protein: Pgp
Summary
InnateDB Protein IDBP-146799.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pgp
Protein Name phosphoglycolate phosphatase
Synonyms 1700012G19Rik; AI481330; AUM;
Species Mus musculus
Ensembl Protein ENSMUSP00000052866
InnateDB Gene IDBG-146797 (Pgp)
Protein Structure
UniProt Annotation
Function Phosphatase with broad substrate specificity. Has high phosphatase activity toward ADP, ATP, GDP, GTP and p- nitrophenylphosphate. Has tyrosine-protein phosphatase activity (in vitro). Has very low activity with pyridoxal 5'-phosphate.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous. Highly expressed in testis (at protein level). {ECO:0000269PubMed:24338473}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004725 protein tyrosine phosphatase activity
GO:0008967 phosphoglycolate phosphatase activity
GO:0016791 phosphatase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0008152 metabolic process
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1914328
InterPro IPR006349 2-phosphoglycolate phosphatase, eukaryotic
IPR006357 HAD-superfamily hydrolase, subfamily IIA
IPR023214 HAD-like domain
PFAM PF13344
PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CHP8
PhosphoSite PhosphoSite-Q8CHP8
TrEMBL Q9CVY8
UniProt Splice Variant
Entrez Gene 67078
UniGene
RefSeq NP_080230
MGI ID 4BKM
MGI Symbol Pgp
OMIM
CCDS CCDS28482
HPRD
IMGT
EMBL AK005906 AK010094 BC040100
GenPept AAH40100 BAB24310 BAB26698

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca