Mus musculus Protein: Lcn5 | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-146916.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Lcn5 | ||||||||
Protein Name | lipocalin 5 | ||||||||
Synonyms | E-RABP; Erabp; MEP10; | ||||||||
Species | Mus musculus | ||||||||
Ensembl Protein | ENSMUSP00000097888 | ||||||||
InnateDB Gene | IDBG-146914 (Lcn5) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | Associates with spermatozoa in the epididymal fluid but does not bind tightly to them. Binds both all-trans and 13-cis retinoic acid. May act as a retinoid carrier protein which is required for epididymal function and/or sperm maturation. {ECO:0000269PubMed:1591332, ECO:0000269PubMed:1591333}. | ||||||||
Subcellular Localization | Secreted {ECO:0000269PubMed:1591332, ECO:0000269PubMed:2393684}. Note=Synthesized by the mid and distal caput of the epididymis and secreted into the epididymal lumen. {ECO:0000269PubMed:1591332, ECO:0000269PubMed:2393684}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | Epididymal fluid of the caudal and corpus regions (at protein level). {ECO:0000269PubMed:14595821}. | ||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | MGI:1277241 | ||||||||
InterPro |
IPR000566
Lipocalin/cytosolic fatty-acid binding domain IPR002345 Lipocalin IPR002972 Prostaglandin D synthase IPR011038 Calycin-like |
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PFAM |
PF00061
PF08212 |
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PRINTS |
PR00179
PR01254 |
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PIRSF | |||||||||
SMART | |||||||||
TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | A2AJB7 | ||||||||
PhosphoSite | PhosphoSite- | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 13863 | ||||||||
UniGene | Mm.12867 | ||||||||
RefSeq | NP_001036095 | ||||||||
MGI ID | |||||||||
MGI Symbol | Lcn5 | ||||||||
OMIM | |||||||||
CCDS | CCDS38078 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AK136629 AK162355 AL732590 U68381 U68546 | ||||||||
GenPept | AAC24316 AAD09351 BAE23077 BAE36871 CAM25179 CAM25180 CAM25181 | ||||||||