Version 5.4
| Mus musculus Protein: Lcn5 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-146920.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Lcn5 | ||||||||
| Protein Name | lipocalin 5 | ||||||||
| Synonyms | E-RABP; Erabp; MEP10; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000097887 | ||||||||
| InnateDB Gene | IDBG-146914 (Lcn5) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | Associates with spermatozoa in the epididymal fluid but does not bind tightly to them. Binds both all-trans and 13-cis retinoic acid. May act as a retinoid carrier protein which is required for epididymal function and/or sperm maturation. {ECO:0000269PubMed:1591332, ECO:0000269PubMed:1591333}. | ||||||||
| Subcellular Localization | Secreted {ECO:0000269PubMed:1591332, ECO:0000269PubMed:2393684}. Note=Synthesized by the mid and distal caput of the epididymis and secreted into the epididymal lumen. {ECO:0000269PubMed:1591332, ECO:0000269PubMed:2393684}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Epididymal fluid of the caudal and corpus regions (at protein level). {ECO:0000269PubMed:14595821}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1277241 | ||||||||
| InterPro |
IPR000566
Lipocalin/cytosolic fatty-acid binding domain IPR002345 Lipocalin IPR002972 Prostaglandin D synthase IPR011038 Calycin-like |
||||||||
| PFAM |
PF00061
PF08212 |
||||||||
| PRINTS |
PR00179
PR01254 |
||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A2AJB7 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 13863 | ||||||||
| UniGene | Mm.12867 | ||||||||
| RefSeq | NP_001263186 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Lcn5 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS71003 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK136629 AK162355 AL732590 U68381 U68546 | ||||||||
| GenPept | AAC24316 AAD09351 BAE23077 BAE36871 CAM25179 CAM25180 CAM25181 | ||||||||