InnateDB Protein
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IDBP-14698.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ACRBP
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Protein Name
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acrosin binding protein
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000229243
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InnateDB Gene
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IDBG-14696 (ACRBP)
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Protein Structure
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Function |
May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. {ECO:0000250}.
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Subcellular Localization |
Secreted {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Note=Colocalizes with proacrosin in the acrosome of sperm. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expression restricted to testis in normal tissue. Expressed in a wide spectrum of cancers, including bladder, breast, liver, lung and colon cancers. {ECO:0000269PubMed:11248070}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR009865
Proacrosin binding sp32
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PFAM |
PF07222
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NEB7
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PhosphoSite |
PhosphoSite-Q8NEB7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
84519
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UniGene |
Hs.123239
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RefSeq |
NP_115878
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HUGO |
HGNC:17195
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OMIM |
608352
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CCDS |
CCDS8554
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HPRD |
16322
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IMGT |
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EMBL |
AB051833
BC033010
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GenPept |
AAH33010
BAB39388
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