InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ppic

Summary

InnateDB Protein

IDBP-147012.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppic

Protein Name

peptidylprolyl isomerase C

Synonyms

CyP-20c;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025419

InnateDB Gene

IDBG-147010 (Ppic)

Protein Structure

UniProt Annotation

Function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0005515	protein binding
GO:0042277	peptide binding

Biological Process

GO:0000413	protein peptidyl-prolyl isomerization
GO:0006457	protein folding

Cellular Component

GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:97751

InterPro

IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
IPR029000 Cyclophilin-like domain

PFAM

PF00160

PRINTS

PR00153

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P30412

PhosphoSite

PhosphoSite-

TrEMBL

Q3UC73

UniProt Splice Variant

Entrez Gene

19038

UniGene

Mm.470772

RefSeq

NP_032934

MGI ID

2RMC

MGI Symbol

Ppic

OMIM

CCDS

CCDS29252

HPRD

IMGT

EMBL

AK131931 AK150654 AK151449 AK168911 BC025861 CH466528 M74227

GenPept

AAA37511 AAH25861 BAE20880 BAE29741 BAE30409 BAE40724 EDL09910