InnateDB Protein
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IDBP-147043.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gif
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Protein Name
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gastric intrinsic factor
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Synonyms
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AV073125;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000025585
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InnateDB Gene
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IDBG-147041 (Gif)
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Protein Structure
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Function |
Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Secreted.
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Disease Associations |
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Tissue Specificity |
Gastric mucosa.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1202394
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InterPro |
IPR002157
Cobalamin (vitamin B12)-binding transporter, eukaryotic
IPR019831
Manganese/iron superoxide dismutase, N-terminal
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PFAM |
PF01122
PF00081
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P52787
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
14603
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UniGene |
Mm.456
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RefSeq |
NP_032144
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MGI ID |
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MGI Symbol |
Gif
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OMIM |
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CCDS |
CCDS29609
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HPRD |
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IMGT |
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EMBL |
AK078933
BC118519
CH466534
L24191
L24192
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GenPept |
AAA37881
AAA37882
AAI18520
BAC37468
EDL41439
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