Version 5.4
| Homo sapiens Protein: ADAMTSL5 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-14707.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | ADAMTSL5 | ||||||||
| Protein Name | ADAMTS-like 5 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000327608 | ||||||||
| InnateDB Gene | IDBG-14705 (ADAMTSL5) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May play a role in modulation of fibrillin microfibrils in the extracellular matrix (ECM). | ||||||||
| Subcellular Localization | Secreted {ECO:0000269PubMed:23010571}. Secreted, extracellular space, extracellular matrix {ECO:0000269PubMed:23010571}. Note=Colocalized with fibrillin microfibrils. Predominantly distributed in baso-lateral regions of fibroblast extracellular matrix. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000884
Thrombospondin, type 1 repeat IPR001134 Netrin domain IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold IPR010294 ADAM-TS Spacer 1 IPR013273 Peptidase M12B, ADAM-TS IPR018933 Netrin module, non-TIMP type |
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| PFAM |
PF00090
PF05986 PF01759 |
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| PRINTS |
PR01857
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| PIRSF | |||||||||
| SMART |
SM00209
SM00643 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | X6R4H8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 339366 | ||||||||
| UniGene | Hs.664236 | ||||||||
| RefSeq | NP_998769 | ||||||||
| HUGO | HGNC:27912 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS12071 | ||||||||
| HPRD | 15504 | ||||||||
| IMGT | |||||||||
| EMBL | AC027307 BC139833 | ||||||||
| GenPept | AAI39834 | ||||||||