Version 5.4
Homo sapiens Protein: PRM1
Summary
InnateDB Protein IDBP-14710.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRM1
Protein Name protamine 1
Synonyms CT94.1; P1;
Species Homo sapiens
Ensembl Protein ENSP00000310515
InnateDB Gene IDBG-14708 (PRM1)
Protein Structure
UniProt Annotation
Function Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
Subcellular Localization Nucleus. Chromosome.
Disease Associations
Tissue Specificity Testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006323 DNA packaging
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0030261 chromosome condensation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000221 Protamine P1
PFAM PF00260
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P04553
PhosphoSite PhosphoSite-P04553
TrEMBL Q3MN80
UniProt Splice Variant
Entrez Gene 5619
UniGene
RefSeq NP_002752
HUGO HGNC:9447
OMIM 182880
CCDS CCDS10547
HPRD 01688
IMGT
EMBL AB281136 AF215707 AK311987 AY651260 BC003673 BT006746 CH471112 M29706 M60331 S68144 U15422 Y00443 Z46940
GenPept AAA60191 AAA63249 AAB29321 AAC50486 AAF34620 AAH03673 AAP35392 AAX35688 BAF36637 BAG34926 CAA68499 CAA87065 EAW85157

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca