InnateDB Protein
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IDBP-147188.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gng8
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Protein Name
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guanine nucleotide binding protein (G protein), gamma 8
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Synonyms
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G(y)8;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000077314
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InnateDB Gene
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IDBG-147186 (Gng8)
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Protein Structure
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Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. This subunit may have a very specific role in the development and turnover of olfactory and vomeronasal neurons.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:109163
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InterPro |
IPR001770
G-protein, gamma subunit
IPR015898
G-protein gamma-like domain
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PFAM |
PF00631
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PRINTS |
PR00321
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PIRSF |
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SMART |
SM00224
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TIGRFAMs |
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Modification |
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SwissProt |
P63078
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q3UMY0
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UniProt Splice Variant |
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Entrez Gene |
14709
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UniGene |
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RefSeq |
NP_034450
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MGI ID |
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MGI Symbol |
Gng8
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OMIM |
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CCDS |
CCDS20856
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HPRD |
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IMGT |
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EMBL |
AF188180
AK144609
CH466654
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GenPept |
AAF04570
BAE25968
EDL42072
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