InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rtn1

Summary

InnateDB Protein

IDBP-147377.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rtn1

Protein Name

reticulon 1

Synonyms

Nsp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000077594

InnateDB Gene

IDBG-147375 (Rtn1)

Protein Structure

UniProt Annotation

Function

May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000269PubMed:12036513}; Multi-pass membrane protein {ECO:0000269PubMed:12036513}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0008150	biological_process
GO:0030182	neuron differentiation

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1933947

InterPro

IPR003388 Reticulon

PFAM

PF02453

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K0T0

PhosphoSite

PhosphoSite-Q8K0T0

TrEMBL

Q4FJL2

UniProt Splice Variant

Entrez Gene

104001

UniGene

Mm.221275

RefSeq

NP_703187

MGI ID

MGI Symbol

Rtn1

OMIM

CCDS

CCDS25968

HPRD

IMGT

EMBL

AB074899 AK132364 BC027091 BC030455 BC053926 BC058579 BK001694 CH466526 CT010392

GenPept

AAH27091 AAH30455 AAH53926 AAH58579 BAB96551 BAE21127 CAJ18599 DAA01939 EDL36535