Version 5.4
Mus musculus Protein: Liph
Summary
InnateDB Protein IDBP-147621.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Liph
Protein Name lipase, member H
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000062310
InnateDB Gene IDBG-147619 (Liph)
Protein Structure
UniProt Annotation
Function Hydrolyzes specifically phosphatidic acid (PA) to produce lysophosphatidic acid (LPA). {ECO:0000250}.
Subcellular Localization Secreted. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in placenta and colon. Weakly expressed in small intestine. {ECO:0000269PubMed:12213196}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004620 phospholipase activity
GO:0008201 heparin binding
Biological Process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2388029
InterPro IPR000734 Lipase
IPR008976 Lipase/lipooxygenase, PLAT/LH2
IPR013818 Lipase, N-terminal
IPR016272 Lipoprotein lipase, LIPH
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00151
PRINTS PR00821
PIRSF PIRSF000865
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CIV3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 239759
UniGene Mm.33192
RefSeq NP_001276511
MGI ID
MGI Symbol Liph
OMIM
CCDS CCDS37296
HPRD
IMGT
EMBL AK048150 AK134352 AK136503 AK161067 AK162492 AY093499 BC037489
GenPept AAH37489 AAM18804 BAC33259 BAE22108 BAE23014 BAE36182 BAE36944

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca