Version 5.4
Mus musculus Protein: St3gal4
Summary
InnateDB Protein IDBP-147926.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol St3gal4
Protein Name ST3 beta-galactoside alpha-2,3-sialyltransferase 4
Synonyms Siat4c;
Species Mus musculus
Ensembl Protein ENSMUSP00000034537
InnateDB Gene IDBG-147924 (St3gal4)
Protein Structure
UniProt Annotation
Function It may catalyze the formation of the NeuAc-alpha-2,3- Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. {ECO:0000250}.
Subcellular Localization Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity
GO:0005515 protein binding
GO:0008373 sialyltransferase activity
GO:0047288 monosialoganglioside sialyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0050890 cognition
GO:0097503 sialylation
Cellular Component
GO:0016020 membrane
GO:0030173 integral component of Golgi membrane
GO:0032580 Golgi cisterna membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1316743
InterPro IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase
PFAM PF00777
PRINTS
PIRSF PIRSF005557
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91Y74
PhosphoSite PhosphoSite-Q91Y74
TrEMBL
UniProt Splice Variant
Entrez Gene 20443
UniGene Mm.391926
RefSeq NP_033204
MGI ID
MGI Symbol St3gal4
OMIM
CCDS CCDS22956
HPRD
IMGT
EMBL AB061305 BC050773
GenPept AAH50773 BAB47508

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca