Version 5.4
Mus musculus Protein: Myo1g
Summary
InnateDB Protein IDBP-147929.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myo1g
Protein Name myosin IG
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000003459
InnateDB Gene IDBG-147927 (Myo1g)
Protein Structure
UniProt Annotation
Function Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:20071333}; Peripheral membrane protein {ECO:0000269PubMed:20071333}. Note=Localization at the membrane is not highly dependent on phosphatidylinositol 4,5-bisphosphate levels (By similarity). Released from the membrane in the presence of ATP (By similarity). May be enriched in pripheral processes, such as microvilli or ruffles. {ECO:0000250}.
Disease Associations
Tissue Specificity Specifically expressed in hematopoietic cells. {ECO:0000269PubMed:20071333}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016459 myosin complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1927091
InterPro IPR001609 Myosin head, motor domain
IPR010926 Myosin tail 2
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00063
PF06017
PRINTS PR00193
PIRSF
SMART SM00242
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SUA5
PhosphoSite PhosphoSite-Q5SUA5
TrEMBL
UniProt Splice Variant
Entrez Gene 246177
UniGene Mm.482316
RefSeq NP_848534
MGI ID
MGI Symbol Myo1g
OMIM
CCDS CCDS24421
HPRD
IMGT
EMBL AF426468 AK030825 AK042033 AK088011 AL646047 BC028661
GenPept AAH28661 AAL26548 BAC27149 BAC31139 BAC40093 CAI25989

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca