InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hoxa7

Summary

InnateDB Protein

IDBP-147981.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hoxa7

Protein Name

homeobox A7

Synonyms

AV118143; Hox-1.1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000048648

InnateDB Gene

IDBG-147979 (Hoxa7)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	2 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008134	transcription factor binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001525	angiogenesis
GO:0001953	negative regulation of cell-matrix adhesion
GO:0002686	negative regulation of leukocyte migration
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0009952	anterior/posterior pattern specification
GO:0045617	negative regulation of keratinocyte differentiation
GO:0045656	negative regulation of monocyte differentiation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048704	embryonic skeletal system morphogenesis
GO:0048863	stem cell differentiation