InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Etv5

Summary

InnateDB Protein

IDBP-148155.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Etv5

Protein Name

ets variant gene 5

Synonyms

1110005E01Rik; 8430401F14Rik; ERM;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000078551

InnateDB Gene

IDBG-148153 (Etv5)

Protein Structure

UniProt Annotation

Function

Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00237}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	2 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0007274	neuromuscular synaptic transmission
GO:0007626	locomotory behavior
GO:0030154	cell differentiation
GO:0034599	cellular response to oxidative stress
GO:0045666	positive regulation of neuron differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048133	male germ-line stem cell division
GO:0050807	regulation of synapse organization
GO:0060252	positive regulation of glial cell proliferation
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis
GO:0071340	skeletal muscle acetylcholine-gated channel clustering