InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rtn4ip1

Summary

InnateDB Protein

IDBP-148364.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rtn4ip1

Protein Name

reticulon 4 interacting protein 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000060940

InnateDB Gene

IDBG-148362 (Rtn4ip1)

Protein Structure

UniProt Annotation

Function

Appears to be a potent inhibitor of regeneration following spinal cord injury. {ECO:0000269PubMed:12067236}.

Subcellular Localization

Mitochondrion {ECO:0000269PubMed:12067236}.

Disease Associations

Tissue Specificity

Widely expressed in mitochondria-enriched tissues. Found in heart, kidney, liver, brain and spinal cord. {ECO:0000269PubMed:12067236}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008270	zinc ion binding
GO:0016491	oxidoreductase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

MGI:2178759

InterPro

IPR011032 GroES (chaperonin 10)-like
IPR013149 Alcohol dehydrogenase, C-terminal
IPR013154 Alcohol dehydrogenase GroES-like
IPR020843 Polyketide synthase, enoylreductase

PFAM

PF00107
PF08240

PRINTS

PIRSF

SMART

SM00829

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q924D0