InnateDB Protein
|
IDBP-148376.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Mboat4
|
Protein Name
|
membrane bound O-acyltransferase domain containing 4
|
Synonyms
|
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000092988
|
InnateDB Gene
|
IDBG-148374 (Mboat4)
|
Protein Structure
|
|
Function |
Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid. {ECO:0000269PubMed:18267071, ECO:0000269PubMed:18443287}.
|
Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:18267071}; Multi-pass membrane protein {ECO:0000269PubMed:18267071}.
|
Disease Associations |
|
Tissue Specificity |
Highly expressed in stomach. Lower expression in small intestine and colon. Very low expression in testis. {ECO:0000269PubMed:18267071}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
Accession |
GO Term |
GO:0016412
|
serine O-acyltransferase activity
|
|
Biological Process |
|
Cellular Component |
GO:0030176
|
integral component of endoplasmic reticulum membrane
|
|
PDB ID |
MGI:2685017
|
InterPro |
IPR004299
Membrane bound O-acyl transferase, MBOAT
|
PFAM |
PF03062
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P0C7A3
|
PhosphoSite |
PhosphoSite-P0C7A3
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
234155
|
UniGene |
Mm.324008
|
RefSeq |
NP_001119786
|
MGI ID |
|
MGI Symbol |
Mboat4
|
OMIM |
|
CCDS |
CCDS52540
|
HPRD |
|
IMGT |
|
EMBL |
AC167537
BC147844
BC147849
EU518496
EU721729
|
GenPept |
AAI47845
AAI47850
ACB05874
ACD93144
|
|
|