Version 5.4
Mus musculus Protein: Leprotl1
Summary
InnateDB Protein IDBP-148394.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Leprotl1
Protein Name leptin receptor overlapping transcript-like 1
Synonyms 1110067H13Rik; 1520402O14Rik; AI854296;
Species Mus musculus
Ensembl Protein ENSMUSP00000033910
InnateDB Gene IDBG-148392 (Leprotl1)
Protein Structure
UniProt Annotation
Function Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. {ECO:0000269PubMed:19907080}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1915442
InterPro IPR007262 Vacuolar protein sorting 55
PFAM PF04133
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CQ74
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 68192
UniGene Mm.473007
RefSeq NP_080885
MGI ID
MGI Symbol Leprotl1
OMIM
CCDS CCDS22239
HPRD
IMGT
EMBL AK003329 AK013870 AK075740 AK150289 AK153277 AK159401 BC004677
GenPept AAH04677 BAB22717 BAB29025 BAC35921 BAE29444 BAE31863 BAE35053

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca