Version 5.4
Homo sapiens Protein: PIANP
Summary
InnateDB Protein IDBP-14856.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIANP
Protein Name chromosome 12 open reading frame 53
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000317818
InnateDB Gene IDBG-14854 (PIANP)
Protein Structure
UniProt Annotation
Function Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation. {ECO:0000269PubMed:21241660}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Mainly expressed in adult brain and cerebellum. Weaker expression in fetal brain and virtually no expression in spleen, heart, kidney, liver and dorsal ganglion relative to brain. {ECO:0000269PubMed:21241660}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IYJ0
PhosphoSite PhosphoSite-
TrEMBL F5H191
UniProt Splice Variant
Entrez Gene 196500
UniGene Hs.44067
RefSeq NP_710152
HUGO HGNC:25338
OMIM
CCDS CCDS44818
HPRD 13205
IMGT
EMBL AC125494 AK056295 AK091656 AK095854 AK289648 AY358534 BC035736 CH471116
GenPept AAH35736 AAQ88898 BAF82337 BAG51669 BAG52398 BAG53145 EAW88750 EAW88751

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca