Version 5.4
Mus musculus Protein: Tbccd1
Summary
InnateDB Protein IDBP-148579.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbccd1
Protein Name TBCC domain containing 1
Synonyms 5730478M09Rik; AU015083; BB165076;
Species Mus musculus
Ensembl Protein ENSMUSP00000004576
InnateDB Gene IDBG-148577 (Tbccd1)
Protein Structure
UniProt Annotation
Function Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=Localizes at the spindle midzone, midbody and basal bodies of primary and motile cilia. {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain and testis (at protein level). {ECO:0000269PubMed:20168327}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
Biological Process
GO:0000902 cell morphogenesis
GO:0007010 cytoskeleton organization
GO:0008360 regulation of cell shape
GO:0030334 regulation of cell migration
GO:0051661 maintenance of centrosome location
GO:0051684 maintenance of Golgi location
Cellular Component
GO:0005737 cytoplasm
GO:0031616 spindle pole centrosome
Protein Structure and Domains
PDB ID MGI:1917823
InterPro IPR006599 CARP motif
IPR012945 Tubulin binding cofactor C-like domain
PFAM PF07986
PRINTS
PIRSF
SMART SM00673
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q640P7
PhosphoSite PhosphoSite-Q640P7
TrEMBL
UniProt Splice Variant
Entrez Gene 70573
UniGene
RefSeq NP_001074837
MGI ID
MGI Symbol Tbccd1
OMIM
CCDS CCDS49798
HPRD
IMGT
EMBL AK017705 AK039905 AK043059 BC079629 BC082558
GenPept AAH79629 AAH82558 BAB30885 BAC30476 BAC31450

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca