Version 5.4
Mus musculus Protein: Slitrk4
Summary
InnateDB Protein IDBP-149064.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slitrk4
Protein Name SLIT and NTRK-like family, member 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000064443
InnateDB Gene IDBG-149062 (Slitrk4)
Protein Structure
UniProt Annotation
Function Suppresses neurite outgrowth. {ECO:0000269PubMed:14550773}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity In the adult, significant expression is detected only in the brain. Broadly expressed in embryonic brain with highest expression in subventricular zone, subplate, cortical plate, pyramidal cell layer of hippocampus, thalamus and hypothalamus. {ECO:0000269PubMed:14550773}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007409 axonogenesis
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2442509
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01463
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00082
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q810B8
PhosphoSite PhosphoSite-Q810B8
TrEMBL Q8BL04
UniProt Splice Variant
Entrez Gene 245446
UniGene Mm.407609
RefSeq NP_848855
MGI ID
MGI Symbol Slitrk4
OMIM
CCDS CCDS30167
HPRD
IMGT
EMBL AB097573 AK032263 AK039763 AK047626 AK053065 AL669956 BC117890 BC117891 CH466583
GenPept AAI17891 AAI17892 BAC27786 BAC30442 BAC33104 BAC35254 BAC67207 EDL42197

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca