InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ppyr1

Summary

InnateDB Protein

IDBP-149154.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppyr1

Protein Name

pancreatic polypeptide receptor 1

Synonyms

NYYR-D; Ppyr1; Y4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000056576

InnateDB Gene

IDBG-149152 (Ppyr1)

Protein Structure

UniProt Annotation

Function

Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP >> PYY >= NPY.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Heart, detected in small intestine.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001601	peptide YY receptor activity
GO:0001602	pancreatic polypeptide receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0042277	peptide binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:105374

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000611 Neuropeptide Y receptor family
IPR001933 Neuropeptide Y4 receptor
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR01012
PR01015

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q61041