Version 5.4
Mus musculus Protein: Gphb5
Summary
InnateDB Protein IDBP-149200.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gphb5
Protein Name glycoprotein hormone beta 5
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000061488
InnateDB Gene IDBG-149198 (Gphb5)
Protein Structure
UniProt Annotation
Function Stimulates the thyroid. Binds and activates THSR, leading to increased cAMP production (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in the anterior lobe of pituitary.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005179 hormone activity
Biological Process
GO:0002155 regulation of thyroid hormone mediated signaling pathway
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:2156540
InterPro IPR001545 Gonadotropin, beta subunit
IPR006208 Glycoprotein hormone subunit beta, cystine knot
IPR029034 Cystine-knot cytokine
PFAM PF00007
PRINTS
PIRSF
SMART SM00068
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q812B2
PhosphoSite PhosphoSite-
TrEMBL Q2NL39
UniProt Splice Variant
Entrez Gene 217674
UniGene Mm.252250
RefSeq NP_783575
MGI ID
MGI Symbol Gphb5
OMIM
CCDS CCDS25982
HPRD
IMGT
EMBL AF467771 AK078727 BC111115 BC139462 BC139463 CH466526
GenPept AAI11116 AAI39463 AAI39464 AAO33391 EDL36488

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca