Mus musculus Protein: Nubp2 | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-149553.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Nubp2 | ||||||||||
Protein Name | nucleotide binding protein 2 | ||||||||||
Synonyms | D17Wsu11e; | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Protein | ENSMUSP00000049319 | ||||||||||
InnateDB Gene | IDBG-149551 (Nubp2) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. {ECO:0000255HAMAP-Rule:MF_03039}. | ||||||||||
Subcellular Localization | Nucleus {ECO:0000255HAMAP-Rule:MF_03039, ECO:0000269PubMed:16638812}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255HAMAP-Rule:MF_03039, ECO:0000269PubMed:16638812}. Note=Enriched at the centrosomes during mitosis. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | Widely expressed. | ||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | MGI:1347072 | ||||||||||
InterPro |
IPR002586
CobQ/CobB/MinD/ParA nucleotide binding domain IPR005129 ArgK protein IPR015223 ATPase MipZ/NubP2/Cfd1 IPR019591 ATPase-like, ParA/MinD IPR025723 Anion-transporting ATPase-like domain IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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PFAM |
PF01656
PF03308 PF09140 PF10609 PF02374 |
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PRINTS | |||||||||||
PIRSF | |||||||||||
SMART | |||||||||||
TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q9R061 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 26426 | ||||||||||
UniGene | Mm.36718 | ||||||||||
RefSeq | NP_036086 | ||||||||||
MGI ID | |||||||||||
MGI Symbol | Nubp2 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS28500 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AF114169 AK003816 BC012635 | ||||||||||
GenPept | AAF01785 AAH12635 BAB23013 | ||||||||||