Version 5.4
Homo sapiens Protein: ZFY
Summary
InnateDB Protein IDBP-15.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZFY
Protein Name zinc finger protein, Y-linked
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000155093
InnateDB Gene IDBG-11 (ZFY)
Protein Structure
UniProt Annotation
Function Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3'. {ECO:0000269PubMed:20028140}.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR006794 Transcriptional activator, Zfx / Zfy domain
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF04704
PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08048
PhosphoSite PhosphoSite-P08048
TrEMBL C9JQM1
UniProt Splice Variant
Entrez Gene 7544
UniGene Hs.522845
RefSeq NP_003402
HUGO HGNC:12870
OMIM 490000
CCDS CCDS14774
HPRD 02466
IMGT
EMBL AC006157 AF114156 AK301061 BC114526 BC114960 L10393 M30607 X15470
GenPept AAA61310 AAA72344 AAD15612 AAF21973 AAI14527 AAI14961 BAG62669 CAA33498

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca