Version 5.4
| Mus musculus Protein: Svep1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-150092.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Svep1 | ||||||||
| Protein Name | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | ||||||||
| Synonyms | 1110021D17Rik; 4833413O10Rik; AA387071; D430029O09Rik; Polydom; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000045856 | ||||||||
| InnateDB Gene | IDBG-150088 (Svep1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May play a role in the cell attachment process. | ||||||||
| Subcellular Localization | Secreted {ECO:0000305}. Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Present in stromal osteogenic cells. Expressed at much higher level in stromal osteogenic cells at low density compared to cells grown at higher densities (at protein level). Highly expressed in lung and placenta. Also expressed in bone and periosteum, but not in cartilage and skeletal muscle. Weakly or not expressed in other tissues. {ECO:0000269PubMed:11062057, ECO:0000269PubMed:16206243}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1928849 | ||||||||
| InterPro |
IPR000436
Sushi/SCR/CCP IPR000742 Epidermal growth factor-like domain IPR001759 Pentaxin IPR001881 EGF-like calcium-binding domain IPR002035 von Willebrand factor, type A IPR003410 Hyalin IPR008985 Concanavalin A-like lectin/glucanases superfamily IPR009030 Insulin-like growth factor binding protein, N-terminal IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like IPR013111 EGF-like domain, extracellular |
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| PFAM |
PF00084
PF00008 PF00354 PF07645 PF00092 PF02494 PF07699 PF07974 |
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| PRINTS |
PR00895
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| PIRSF | |||||||||
| SMART |
SM00032
SM00181 SM00159 SM00179 SM00327 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A2AVA0 | ||||||||
| PhosphoSite | PhosphoSite-A2AVA0 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 64817 | ||||||||
| UniGene | Mm.412348 | ||||||||
| RefSeq | NP_073725 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Svep1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS18209 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF206329 AK014693 AK035333 AK052699 AL805969 AL929406 BC008135 | ||||||||
| GenPept | AAG32160 AAH08135 BAB29505 BAC29036 BAC35103 CAM21214 CAM23597 | ||||||||