InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ercc5

Summary

InnateDB Protein

IDBP-150477.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ercc5

Protein Name

excision repair cross-complementing rodent repair deficiency, complementation group 5

Synonyms

Xpg;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027214

InnateDB Gene

IDBG-150475 (Ercc5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003697	single-stranded DNA binding
GO:0003824	catalytic activity
GO:0004518	nuclease activity
GO:0004519	endonuclease activity

Biological Process

GO:0006281	DNA repair
GO:0006289	nucleotide-excision repair
GO:0008340	determination of adult lifespan
GO:0009411	response to UV
GO:0009650	UV protection
GO:0035264	multicellular organism growth
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:103582

InterPro

IPR001044 XPG/Rad2 endonuclease, eukaryotes
IPR006085 XPG N-terminal
IPR006086 XPG-I domain
IPR008918 Helix-hairpin-helix motif, class 2
IPR020045 5\'-3\' exonuclease, C-terminal domain
IPR029060 PIN domain-like

PFAM

PF00752
PF00867
PF01367
PF09293

PRINTS

PR00066

PIRSF

SMART

SM00485
SM00484
SM00279

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt