Version 5.4
Mus musculus Protein: Gm606
Summary
InnateDB Protein IDBP-150555.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gm606
Protein Name predicted gene 606
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000087269
InnateDB Gene IDBG-150553 (Gm606)
Protein Structure
UniProt Annotation
Function Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2- dependent recruitment of CDC45L onto replication origins (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Note=Associates with chromatin during pre-replication complex (pre-RC) formation. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003682 chromatin binding
Biological Process
GO:0006260 DNA replication
GO:0007049 cell cycle
GO:0008283 cell proliferation
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2685452
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3URY2
PhosphoSite PhosphoSite-Q3URY2
TrEMBL
UniProt Splice Variant
Entrez Gene 239789
UniGene Mm.326909
RefSeq NP_001272847
MGI ID
MGI Symbol Gmnc
OMIM
CCDS CCDS37304
HPRD
IMGT
EMBL AK141059 AK160719 BC086669
GenPept AAH86669 BAE24555 BAE35968

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca