Version 5.4
Mus musculus Protein: AI314180
Summary
InnateDB Protein IDBP-150570.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AI314180
Protein Name expressed sequence AI314180
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000099953
InnateDB Gene IDBG-150568 (AI314180)
Protein Structure
UniProt Annotation
Function Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolyis (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250}. Endosome {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Nucleus {ECO:0000250}. Endosome, multivesicular body {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed at high levels in brain and testis, at low levels in liver, and at very low levels in heart and kidney (at protein level). {ECO:0000269PubMed:15496406}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 61 interaction(s) predicted by orthology.
Predicted by orthology
Total 61 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005771 multivesicular body
GO:0005783 endoplasmic reticulum
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005815 microtubule organizing center
GO:0030139 endocytic vesicle
Protein Structure and Domains
PDB ID MGI:2140220
InterPro IPR016024 Armadillo-type fold
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PDI5
PhosphoSite PhosphoSite-Q6PDI5
TrEMBL Q8C2Z1
UniProt Splice Variant
Entrez Gene 230249
UniGene Mm.409933
RefSeq NP_759013
MGI ID
MGI Symbol AI314180
OMIM
CCDS CCDS18214
HPRD
IMGT
EMBL AK030369 AK038775 AK087690 AK129127 AL805972 AL806535 AL929394 BC025035 BC058684
GenPept AAH25035 AAH58684 BAC26926 BAC30129 BAC39969 BAC97937 CAM17649 CAM22037 CAM24807

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca